Marble Anion Gap

Recent evidence 3 indicates that diabetic ketoacido sis should no longer be viewed simply as wide anion gap metabolic acidosis.

Marble anion gap.

Ever wondered what on earth the anion gap was all about. A retrospective study of 6868 sets of serum electrolytes among hospitalized patients 3 for example revealed incidences of increased and reduced anion gap to be 37 6 and 2 9 respectively. Killu and sarani 2016 fundamental critical care support p. Anion gap decreases 2 5 meq per 1 g dl albumin drop.

Abnormal anion gap is a relatively common occurrence among hospitalized patients with increased anion gap being far more common than reduced anion gap. But when you ve got yourself a metabolic acidosis this is a good place to start. I was just tasked with adding anion gap to our panels. Metabolic acidosis with high anion gap without increased serum chloride severe alkalemia albumin become negatively charged references.

Moreover as confirmed in this pa tient diabetic ketoacidosis may present with pure hy perchloremic acidosis. An increased anion gap 16 is observed in many inborn errors of metabolism and in most other conditions producing metabolic acidosis in the neonate. Thus the finding of a normal anion gap per se may not exclude the presence of diabetic ketoacidosis.